Laparoscopy / Adhesion Prevention

OXIPLEX®/IU for Intrauterine Adhesions

Adhesion barriers are a proven method of enhancing good surgical technique by reducing post-surgical adhesions. Intrauterine (IU) adhesions are bands of scar tissue that form between the inner walls of the uterus and are common following dilation & curattage, pregnancy termination and intrauterine surgical procedures. IU Adhesions cause problems such as infertility, pain and discomfort, menstrual cycle abnormalities, dysmenorrhea and recurrent pregnancy loss.

Efficacious, Easy to Use and Precise

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Brochures

OXIPLEX ADHESION BARRIER GEL – EXCEPTIONAL CLINICAL RESULTS

Di Spiezio Sardo et al used Oxiplex/AP following hysteroscopic metroplasty to expand dysmorphic uteri in a prospective, observational study in 30 infertile women.

  • Oxiplex/AP gel was applied into the uterine cavity at the completion of the procedure through the in ow channel of the hysteroscope.
  • At the mean follow-up of 15 months, clinical pregnancy rate was 57% and term delivery rate was 65%.
  • Low incidence of post surgical synechiae attributed to the use of Oxiplex/AP gel.

Di Spiezio Sardo et al used Oxiplex/AP following hysteroscopic surgery in a randomized study of 110 patients.

  • Follow-up at one month showed that Oxiplex/AP treated patients had fewer ‘de novo’ adhesions (6% vs 22%) compared to control.
  • Patients treated with Oxiplex/AP also demonstrated improvement in the degree of patency of the internal uterine osteum.

Fuchs et al. used Oxiplex/AP following hysteroscopic surgery in a randomized study of 52 women.

  • Follow up at 20 months showed that Oxiplex/AP treated patients had fewer moderate to severe intra-uterine adhesions (4% vs 14%) compared to control.
  • Patients treated with Oxiplex/AP had an improved fertility rate (27% vs 14%) compared to controls.

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